Updating Mac OS X to 10.4.10 also updates QuickTime to 7.2, which if your on an Intel Mac will very likely cause all your Rosseta applications to stop working. There is an official fix which is not only involved, but it sometimes does not work. You might get this error when running update_prebinding:
dyld: re-prebound: 0x90bee000 /usr/lib/libgcc_s.1.dylib
update_prebinding: error: dependent dylib is not prebound
update_prebinding: error 256 running update_prebinding_core
Then you need to follow the instructions here.
Some people in the Apple QA team should get a kick in the balls for this.